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We guessed that it was going to rise that way, but we didnt know, Sherer said. Much more painful was the obvious morbidity and mortality. Single- and double-drug therapies were introduced but only added 12 to 24 months of life expectancy. They were helpful and kept people alive, but only for a while, said Sherer. This continued until 1996, when researchers at the Vancouver AIDS Conference announced the effectiveness of protease-inhibiting multi-drug therapy.